Men are starting to think that Tadalista 20 is the best medicine for erectile dysfunction that is out there. The primary component of this medication is tadalafil. Tadalafil belongs to the group of drugs called phosphodiesterase 5 inhibitors. These drugs cause phosphodiesterase type-5 to stop working too soon. The penis is one area where this enzyme is active. After taking this drug, avoid having a big meal or eating foods high in fat. It might make the drug less effective. You cannot take the drug with grapefruit juice, alcohol, or coffee. Tadalista 20 often takes 30 to 60 minutes to start working. Tadalafil, the medication's active component, improves blood flow to the penis and aids in achieving and maintaining an erection.